L-Cysteine HCl | Monohydrate & Anhydrous | CAS 7048-04-6 & 52-89-1 - - PREMIUM INGREDIENT

L-Cysteine Hcl Monohydrate CAS 7048-04-6 | L-Cysteine Hcl Anhydrous Cas 52-89-1 | E920 | Amino Acid for Food, Pharmaceutical and Cosmetic Use

Categories:

Amino Acids

CAS No:

4 / 1

Description

Certificates

Basic Info

Characteristics

Hazard Identification

Handling and Storage

Basic Information

Item	L-Cysteine HCl Monohydrate	L-Cysteine HCl Anhydrous
Product Name	L-Cysteine Hydrochloride Monohydrate	L-Cysteine Hydrochloride Anhydrous
CAS No.	7048-04-6	52-89-1
E Number	E920	E920
Other Name	L-Cys HCl Monohydrate	L-Cys HCl Anhydrous
Grade	Food Grade,	Food Grade, Pharmaceutical Grade
Purity	≥98.5%	≥98.5%
molecular formula	C₃H₇NO₂S·HCl·H₂O	C₃H₇NO₂S·HCl
implementation standard	AJI/USP/EP/CP	AJI/USP/EP/CP
Solubility	Highly soluble in water	Highly soluble in water
Storage	Cool, dry, sealed, protected from moisture	Cool, dry, sealed, protected from moisture

Product Overview

L-Cysteine Hydrochloride is a sulfur-containing L-form protein amino acid with strong reducing properties, acting as a precursor for glutathione and delivering antioxidant functions. It is widely applied across food, pharmaceutical and cosmetic industries. In food production, it serves as E920 dough conditioner to improve dough extensibility and baked goods texture, while also working as antioxidant and flavor precursor for savory food formulations. For pharmaceutical industry, it acts as a key raw material for drug preparations. In cosmetic field, it functions on keratin structure for hair and skincare formulations. It is available in two forms: l-cysteine hydrochloride monohydrate (CAS 7048-04-6) and l-cysteine hydrochloride anhydrous (CAS 52-89-1).

L-Cysteine Hydrochloride Anhydrous, CAS No.: 52-89-1, Molecular Formula: C₃H₇NO₂S·HCl, the content of moisture is 1.0% max, Making it suitable for pharma formulations and low-water formula systems that require strict moisture control. Such as in flour processing, it acts as a flour reducing agent and bread fermentation accelerator. It relaxes gluten and accelerates gluten formation to optimize dough processability and finished product quality.

L-Cysteine HCl Monohydrate, Cas No.: 7048-04-6, Molecular Formula: C₃H₇NO₂S·HCl.H2O, The content of moisture is 8.5%-12.0%. is widely preferred for general food and cosmetic formulations. It is the key raw material for synthesizing N-Acetyl-L-Cysteine (NAC). In food systems, it works as a flavor enhancer.

Key Characteristics

Feature	Monohydrate	Anhydrous
Water content	8.5%-12.0%	1.0% max
Solubility	Highly soluble in water	Highly soluble in water
Core strength	Raw material for NAC synthesis; excellent savory flavor enhancer	Strong reducibility, flour reducing agent & fermentation accelerator; low moisture, stable crystalline granules

Main Function

L-Cysteine hcl monohydrate &Anhydrous

1. Acts as dough conditioner, antioxidant and flavor precursor for food production

2.Serves as key amino acid raw material for pharmaceutical formulations

3. Functions as reducing ingredient for cosmetic hair and skincare formulations

L-Cysteine HCl Monohydrate

Synthesis precursor: Major starting raw material for manufacturing N-Acetyl-L-Cysteine (NAC).

L-Cysteine HCl Anhydrous

1.Flour reducing agent and bread fermentation accelerator: Relaxes gluten and accelerates gluten formation, improving dough processing performance and finished product quality.

Application

Food: Primary application, dough conditioning for bakery, antioxidant and savory flavor generation; Monohydrate is the common choice

Pharmaceutical: Raw material for pharmaceutical intermediates and preparations; Anhydrous is preferred for formulas requiring low moisture

Cosmetic: Functional raw material for hair treatment and skincare cosmetic products; Monohydrate is widely adopted

Packaging and Storage

Item	Detail
Packaging	25 kg fiber drum or paper bag
Storage Condition	Store in cool, dry and well-ventilated area
Handling	Keep container tightly sealed, protected from moisture and direct sunlight
Shelf Life	24 months when properly stored

CERTIFICATE OF ANALYSIS

Product: L-Cysteine HCL Anhydrous (Non-animal Source) CAS No: (52-89-1) Quantity: 1000KG Lot No: Date: JAN 05,2025
Item	Specification	Result
Appearance	White crystalline powder	conform
Identification	Infrared absorption	conform
Specific rotation [α]D20	+5.6 to +8.9°	+7.0°
Stateof solution (Transmittance)	Clear and colorless Not less than 98.0 %	99.8%
Chloride(Cl)	22.20 to 22.60 %	22.43%
Ammonium(NH4)	Not more than 0.02 %	<0.02 %
Sulfate(SO4)	Not more than 0.02 %	<0.020 %
Iron(Fe)	Not more than 10ppm	<10ppm
Heavy metals(Pb)	Not more than 10ppm	<10ppm
Arsenic(as As2o3)	Not more than 1ppm	<1ppm
Other amino acids	Chromatographically Not detectable	conforms
Loss on Drying	Not more than 1.0 %	0.41%
Residue on ignition(sulfated)	Not more than 0. 1 %	0.06%
Assay	98.0 to 102.0 %	100. 1%
PH	1.5 to 2.0	1.8

Conclusion : Agree with the specification of AJI92.

Product Name:	L-(+)-Cysteine hydrochloride	Other Name:	L-Cysteine,hydrochloride (1:1);Cysteine,hydrochloride,L-;L-Cysteine,hydrochloride;Cysteine chlorohydrate;Cysteine hydrochloride;Cystein chloride;L-(+)-Cysteine hydrochloride;(R)-Cysteine hydrochloride;WR 348;(R)-1-Carboxy-2-mercaptoethanaminium chloride;CSKE 200;(2R)-2-Amino-3-sulfanylpropanoic acid hydrochloride;122641-75-2;122882-13-7;124558-06-1;29844-56-2
CAS No.:	52-89-1	Molecular Formula:	C3H7NO2S.ClH
InChIKeys:	InChIKey=IFQSXNOEEPCSLW-DKWTVANSSA-N	Molecular Weight:	157.61900
Exact Mass:	156.99600	EC Number:	200-157-7
UNII:	A9U1687S1S	DSSTox ID:	DTXSID0020367
Color/Form:	Colorless crystals\|White crystals	HScode:	2930909090
Categories:	Amino Acids and Derivatives

PSA:	102.12000	XLogP3:	0.83040
Appearance:	DryPowder	Melting Point:	170-178 °C (decomp)
Boiling Point:	293.9ºC at 760 mmHg	Flash Point:	131.5ºC
Water Solubility:	SOLUBLE	Storage Conditions:	Store at RT.
Vapor Pressure:	6.73X10-7 mm Hg at 25 °C (est)	Toxicity:	LD50 intraperitoneal in mouse: 1250mg/kg
Henrys Law Constant:	Henry’s Law constant = 5.30X10-11 atm-cu m/mol at 25 °C (est)	Dissociation Constants:	pK1 1.71 /carboxylic/; pK2 8.33 /amine/; pK3 10.78 /sulfide/
Experimental Properties:	100 (20 °C) g/100 g H2O /L-Cysteine hydrochloride monohydrate/\|Hydroxyl radical reaction rate constant = 7.96X10-11cu cm/molecule-sec at 25 °C (est)”>Readily oxidizes to form a dimeric amino acid, cystine, in which the two cysteines are linked via a disulfide bridge, a common structural feature in proteins. Amino Acids and Proteins, D.M. Greenberg, Ed. (Charles C. Thomas, Springfield, IL, 1951) 950 pp.\|In neutral or slightly alkaline aqueous solution it is oxidized to cystine by air. More stable in acidic solutions.\|MP (anhydrous): 178 °C (decomposes). Specific optical rotation: +6.53 deg at 25 °C/D (calculated as cysteine) (c = 2 in 5M HCl); solubility >100 (20 °C) g/100 g H2O /L-Cysteine hydrochloride monohydrate/\|Hydroxyl radical reaction rate constant = 7.96X10-11cu cm/molecule-sec at 25 °C (est)

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.