Basic Information
| Vitamin B12 | |
| Product Type | Water-soluble vitamin, cobalamin |
| Available Form | Cyanocobalamin |
| CAS No. | 68-19-9 |
| Physical Form | Dark red crystalline powder |
| Common Specifications | High purity 98% powder; low concentration 1%, 2% powder |
| Grades | Food grade, Feed grade, Pharmaceutical grade |
Product Overview
Cyanocobalamin (Vitamin B12, CAS 68-19-9) is a dark red crystalline powder produced by microbial fermentation with excellent stability for storage and formulation. As a standard nutritional fortification ingredient, it supports red blood cell formation, nervous system health and energy metabolism. It is widely applied in dietary supplements, animal feed, pharmaceutical formulations and functional food fortification.
Compounding Characteristics
1.Dark red crystalline powder, good flowability
2.Slightly soluble in water
3.Excellent stability against temperature changes, suitable for premix blending
4.Compatible with most B-complex vitamin formulations
5.Must be protected from strong light, moisture and high temperature during storage and handling
Main Functions
1.Red Blood Cell Formation Vitamin B12 participates in hematopoiesis, supports normal red blood cell synthesis and helps prevent megaloblastic anemia.
2.Nervous System Health Maintains the normal structure and function of nerve tissue, supports healthy nervous system operation and protects the nerve myelin sheath.
3.Energy Metabolism Support Serves as a key coenzyme in cellular energy metabolism and helps relieve fatigue and weakness.
4.Homocysteine Metabolism Supports balanced healthy homocysteine levels in the body and aids the maintenance of cardiovascular health.
Applications
1.Food & Dietary Supplements: High purity cyanocobalamin is widely used in multivitamin tablets, capsules, sublingual supplements, fortified cereals, dairy products and functional beverages for human nutritional fortification.
2.Animal Feed Low concentration: 1% / 2% premix powder is commonly adopted. It is added into premixes for poultry, swine, ruminants and aquaculture feed to satisfy animals’ vitamin B12 nutritional requirements, promote growth and prevent anemia of livestock and aquatic species.
3.Pharmaceutical & Medical Applications: High purity 98% pharma grade cyanocobalamin serves as raw material for oral vitamin B12 tablets, compound vitamin preparations and injection formulations. Clinically, it helps prevent and treat vitamin B12 deficiency and megaloblastic anemia. It can also be applied for laboratory research and biochemistry reference standards.
Packaging & Storage
Packing: 1kgs/tin
Storage: Cool, dry, dark and ventilated place, keep tightly sealed
Shelf Life: 24 months under proper sealed storage
| Product Name: | Vitamin B12 | Other Name: | Vitamin B12;Anacobin;Betalin 12;Betaline 12;Byladoce;Cobalin;Cotel;Covit;Crystamin;Cyano-B12;Cyanocobalamin;Cyanocobalamine;Cycolamin;Cykobeminet;Cytacon;Cytamen;Cytobion;5,6-Dimethylbenzimidazolyl cyanocobamide;Dobetin;Docemine;Docibin;Docigram;Dodecabee;Dodecavite;Dodex;Ducobee;Duodecibin;Embiol;Emociclina;Eritrone;Erycytol;Erythrotin;Euhaemon;Extrinsic factor;Fresmin;Hemo-b-doze;Hemomin;Hepagon;Hepavis;Hepcovite;Lactobacillus lactis dorner factor;LLD factor;Macrabin;Megalovel;Milbedoce;Nagravon;Normocytin;Pernaemon;Pernaevit;Pernipuron;Plecyamin;Poyamin;Rebramin;Redamina;Redisol;Rhodacryst;Rubesol;Rubramin;Rubripca;Rubrocitol;Sytobex;B-Twelve;B-Twelve Ora;Vibalt;Vibisone;Virubra;Vitarubin;Vita-rubra;Vitral;Cobalamin,cyanide;Cobalamin,cyano-;Cobamin;Cykobemin;Factor II (vitamin);Cobamide,α-5,6-dimethyl-1H-benzimidazolyl-,cyanide;1H-Benzimidazole,5,6-dimethyl-1-(3-O-phosphono-α-D-ribofuranosyl)-,monoester with cobinamide cyanide,inner salt;Cobamide,cyano-5,6-dimethyl-1H-benzimidazole-;Cyano-5,6-dimethylbenzimidazolylcobamide;5,6-Dimethylbenzimidazolyl-Co-cyanocobamide;Vitamin B12 preparation;Betolvex;Cobalamin,cyano-5,6-dimethylbenzimidazole-;CN-B12;Factor II;Depinar;Cobinamide,cyanide,dihydrogen phosphate (ester),inner salt,3′-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole;Hepavit;Docivit;Behepan;Bedoz;Berubigen;Antipernicin;Rubramin PC;Millevit;Berubi;8023-26-5;8039-03-0;11037-08-4;24436-34-8 |
| CAS No.: | 68-19-9 | Molecular Formula: | C63H88CoN14O14P |
| InChIKeys: | InChIKey=FDJOLVPMNUYSCM-SYUKHSAKSA-L | Molecular Weight: | 1355.37000 |
| Exact Mass: | 1354.57000 | EC Number: | 200-680-0 |
| DSSTox ID: | DTXSID7044346 | Color/Form: | Dark red crystals or an amorphous or crystalline red powder|Dark-red crystals or red powder |
| HScode: | 2936260000 | Categories: | Vitamins and Minerals Medicines |
| PSA: | 479.70000 | XLogP3: | 6.57018 |
| Appearance: | red crystalline powder | Melting Point: | 300 °C”>>300 °C |
| Boiling Point: | 300 °C”>>300 °C | Flash Point: | 48.2 °F |
| Water Solubility: | Soluble | Storage Conditions: | 2-8ºC |
| Toxicity: | LD50 intravenous in mouse: 2gm/kg | Specific rotation: | SPECIFIC OPTICAL ROTATION: -59 + or – 9 DEG @ 23 °C 656 NM (DILUTE AQ SOLN) |
| Odor: | Odorless | Taste: | Tasteless |
| PH: | Commercially available cyanocobalamin for injection has a pH of 4.5-7 | Experimental Properties: | Hygroscopic; when exposed to air, may absorb about 12% water; darkens at 210-220 °C; not melted at 300 °C|All vitamin B12 compounds contain the cobalt atom in its trivalent state. There are at least three active forms: cyanobalamin, hydroxycyanobalamin; nitrocobalamin |
Classification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
| Pictogram(s) | No symbol. |
|---|---|
| Signal word |
No signal word |
| Hazard statement(s) |
none |
| Precautionary statement(s) | |
| Prevention |
none |
| Response |
none |
| Storage |
none |
| Disposal |
none |
Other hazards which do not result in classification
no data available
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.