top of page

Basic Information

 

Comparison Item

Thiamine Hydrochloride

(Vitamin B1 Hydrochloride)

Thiamine Mononitrate

(Vitamin B1 Mononitrate)

Product Name Thiamine Hydrochloride Thiamine Mononitrate
CAS No. 67-03-8 532-43-4
Appearance White crystalline powder White crystalline powder
Purity Specification ≥98.5% ≥98.5%
Solubility Freely soluble in water Slightly soluble in water
Hygroscopicity Higher, easy to absorb moisture Low, non-hygroscopic
Stability Good, sensitive to moisture Excellent, stable in multi-vitamin premixes
Grades Food grade, Feed grade, Pharma grade Food grade, Feed grade, Pharma grade
Core Bioactivity Provides vitamin B1 activity Provides vitamin B1 activity
Suitable Formulations Liquid drinks, liquid supplements, aqueous systems Solid tablets, capsules, powder premixes, feed blends

 

Product Overview

Thiamine Hydrochloride (CAS 67-03-8) and Thiamine Mononitrate (CAS 532-43-4), collectively known as Vitamin B1, are white crystalline powders. As an essential water-soluble vitamin and coenzyme, it participates in carbohydrate metabolism and sustains normal nervous system function. Thiamine mononitrate has low hygroscopicity and better stability, while thiamine hydrochloride offers higher water solubility. They are widely used in dietary supplements, fortified foods, beverages and animal nutrition formulations.


 

Character

Thiamine Hydrochloride: White crystalline powder, freely soluble in water. It features high water solubility, suitable for liquid formulations and pharmaceutical applications. It is hygroscopic and sensitive to high humidity.

Thiamine Mononitrate: White crystalline powder, slightly less soluble in water. Compared with Thiamine Hydrochloride, it has lower hygroscopicity and better stability, ideal for dry powder blends and tablet pressing. It can withstand high-temperature processing conditions.


 

Main Functions

 

1.Energy Metabolism Support: Acts as an essential coenzyme, participates in carbohydrate metabolism in the body, helps convert food into usable energy.

2.Nervous System Health: Supports normal nerve function and maintains healthy nervous system.

3.Supports Heart Health: Helps sustain normal cardiac function.

4.Supports Immune Response: Contributes to healthy immune function.

 

Remarks: Both Thiamine Hydrochloride and Thiamine Mononitrate deliver identical vitamin B1 biological activity after absorption. There is no difference in physiological functions. The distinctions are only physical properties rather than functional differences. The selection depends on the formulation type of the end product.


 

Applications

 

1.Dietary Supplements

Thiamine Mononitrate is widely used in solid multivitamin tablets and capsules.

Thiamine Hydrochloride is selected for liquid oral supplements and effervescent formulations.

 

2.Fortified Food & Beverage

Thiamine Hydrochloride is commonly added into functional drinks, liquid nutritional food.

Thiamine Mononitrate is used in cereals, baked goods and solid fortified food.

 

3.Animal Feed Premixes

Thiamine Mononitrate is the dominant grade for feed premixes due to low hygroscopicity and good stability.

Thiamine Hydrochloride can be used in liquid feed additives.

 


 

Packaging & Storage

Packing: 25kg fiber drum with inner polyethylene bag

Storage: Cool, dry, dark and ventilated place, keep tightly sealed

Shelf Life: 24 months under proper sealed storage

 

Product Name: Thiamine nitrate Other Name: Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,nitrate (1:1);Thiamine nitrate (salt);Thiamine nitrate;Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-,nitrate (salt);3-(4-Amino-2-methylpyrimidyl-5-methyl)-4-methyl-5,β-hydroxyethylthiazolium nitrate;Aneurine mononitrate;Betabion mononitrate;Thiamine mononitrate;Vitamin B1 mononitrate;Vitamin B1 nitrate;Aneurine-nitrate;92739-10-1;1210110-58-9
CAS No.: 532-43-4 Molecular Formula: C12H17N4OS.NO3
InChIKeys: InChIKey=UIERGBJEBXXIGO-UHFFFAOYSA-N Molecular Weight: 327.36
Exact Mass: 327.1 EC Number: 208-537-4
UNII: 8K0I04919X DSSTox ID: DTXSID4038762
HScode: 29362200 Categories: Vitamins and Minerals Medicines

PSA: 167 XLogP3: 1.47300
Appearance: white crystal powder Melting Point: 196-200 °C (decomp)
Storage Conditions: 2-8°C

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word

Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.