top of page
| Product Name: | Riboflavin | Other Name: | Riboflavin;Riboflavine;Benzo[g]pteridine,riboflavin deriv.;Beflavine;Flaxain;Hyre;Lactoflavin;Lactoflavine;Ribipca;Riboderm;Vitamin B2;Vitamin G;Flavaxin;6,7-Dimethyl-9-D-ribitylisoalloxazine;Benzo[g]pteridine-2,4(3H,10H)-dione,7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-;Ribosyn;Vitaflavine;Ribotone;Ribovel;Beflavin;Ribocrisina;Vitasan B2;Lactobene;Flavin BB;Russupteridine yellow III;1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol;6,7-Dimethyl-9-ribitylisoalloxazine;E 101;C.I. Food Yellow 15;Food Yellow 15;(-)-Riboflavin;C.I. 50900;E 101 (dye);San Yellow B;NSC 33298;NCI 0033298;D-Ribitol,1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-;7,8-Dimethyl-10-ribitylisoalloxazine;Ricrolin;Riboflavin E101;Riboflavin FP;Riboflavin F;7,8-Dimethyl-10-(1,2,3,4,5-pentahydroxypentyl)benzo[g]pteridine-2,4-dione;130609-39-1;535950-32-4;890044-91-4;1093390-18-1 |
| CAS No.: | 83-88-5 | Molecular Formula: | C17H20N4O6 |
| InChIKeys: | InChIKey=AUNGANRZJHBGPY-SCRDCRAPSA-N | Molecular Weight: | 376.36 |
| Exact Mass: | 376.36 | EC Number: | 201-507-1 |
| ICSC Number: | 1454 | NSC Number: | 758973 |
| DSSTox ID: | DTXSID8021777 | Color/Form: | Fine orange-yellow needles from 2N acetic acid, alcohol, water, or pyridine … three different crystal forms|Orange to yellow crystals or needles |
| HScode: | 29362300 | Categories: | Vitamins and Minerals Medicines |
| PSA: | 161.56000 | XLogP3: | -1.67520 |
| Appearance: | Yellow to orange Powder | Density: | 1.2112 (rough estimate) |
| Melting Point: | 278-279 °C (decomp) | Flash Point: | 9℃ |
| Refractive Index: | -135 ° (C=0.5, JP Method) | Water Solubility: | 0.07 g/L (20 ºC) |
| Storage Conditions: | 2-8°C | Toxicity: | 10 orally, 5.0 s.c., 0.56 i.p. (Unna, Greslin)”>LD50 in rats (g/kg): >10 orally, 5.0 s.c., 0.56 i.p. (Unna, Greslin) |
| Specific rotation: | -135 º (c=5, 0.05 M NaOH) | Odor: | Slight odor |
| Taste: | Bitter | Dissociation Constants: | pKa = 10.2; pKb = 1.7 |
| Experimental Properties: | Visible or ultraviolet radiation of alkaline solutions causes the formation of lumiflavine … whereas irradiation of acid or neutral solutions gives rise to the production of lumichrome … togther with varying amounts of lumiflavine|Sensitive to alkalies; stable to mineral acids in the dark|In solution, riboflavin has an intense greenish-yellow flourescence|In alkaline solution it is readily soluble but quite unstable to heat and to light forming lumiflavin, a fluorescent degradation product. Riboflavin is nore stable to heat in acid solution, particularly from pH 1.0 to 6.5 but upon irradiation forms lumichrome. Riboflavin is readily adsorbed from acid or neutral solution on such agents as frankonite, fuller’s earth, and certain zeolites, and eluted with acetone or pyridine solutions.|For more Other Experimental Properties (Complete) data for Riboflavin (6 total), please visit the HSDB record page. | Physical Dangers: | Dust explosion possible if in powder or granular form, mixed with air. |
Classification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
| Pictogram(s) | No symbol. |
|---|---|
| Signal word |
No signal word |
| Hazard statement(s) |
none |
| Precautionary statement(s) | |
| Prevention |
none |
| Response |
none |
| Storage |
none |
| Disposal |
none |
Other hazards which do not result in classification
no data available
Precautions for safe handling
NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Well closed.Solutions of riboflavin should be protected from air and light. Riboflavin tablets should be stored in tight, light-resistant containers at a temperature less than 40 degrees C, preferably between 15-30 degrees C.