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Basic Information
D-α-Tocopherol Succinate
Alias Natural Vitamin E Succinate Powder
CAS No. 4345-03-3
Active Ingredient Natural D-alpha Tocopherol
Product Grade Food Grade, Pharma Grade (No Feed Grade)
Physical Property Off-white fine free-flowing powder, non-oily
Core Feature Ultra-high stability, anti-oxidation, non-caking, easy tableting
Main Application Dietary supplements, functional fortified food, pharmaceutical raw materials

 

Product Overview

Natural Vitamin E Succinate (D-alpha Tocopheryl Succinate, CAS 4345-03-3) is a premium, fat-soluble form of natural vitamin E with superior stability compared with conventional tocopherol. This esterified vitamin E derivative avoids easy oxidation and maintains stable activity during processing and long-term storage. It features powerful antioxidant properties, effectively protecting cells from oxidative stress. As a high-purity natural nutritional ingredient, it is highly favored in dietary supplement formulations for its excellent stability and natural antioxidant capacity.

 

Product Characteristics

1.Superior stability: Effectively resists oxidation and thermal decomposition, maintains stable activity during processing and long shelf life

2.Non-oily dry powder: No oil precipitation, no caking phenomenon, perfect for tableting and powder blending

3.High bioavailability: Easily hydrolyzed and absorbed in the human body, efficient nutritional supplementation

4.Excellent compatibility: Stable compounding with other vitamins, minerals and nutritional raw materials

5.Pure natural source: Derived from natural plant extraction, safe and compliant for food and pharmaceutical use

 

Main Functions

 

1.High Bioactivity Natural Vitamin E Derivative: Natural D-alpha configuration delivers high biological activity after hydrolysis in the body.

2.Superior Oxidative Stability: Esterified succinate structure resists oxidation during storage and processing, reducing active ingredient loss.

3.Powder Form for Solid Formulations: Dry powder form, easy to incorporate into tablets, hard capsules and powder nutritional blends, no oily handling issues.

4.Nutritional Fortification Ingredient: Used as natural vitamin E source for dietary supplement formulations.

 

Applications

Dietary Supplements The primary application market. Widely used in tablets, hard capsules and composite vitamin powder blends as a natural vitamin E fortification ingredient. The dry powder form is especially suitable for solid dosage formulations and multi-nutrient premixes.

Packaging & Storage

Packaging: 25kg fiber drum with inner food-grade polyethylene bag

Storage: Store in cool, dry, dark and ventilated warehouse, keep tightly sealed, Avoid direct sunlight, high temperature and humid environment, keep away from oxidants

Shelf Life: 24 months under standard sealed storage conditions

 

Product Name: Vitamin E succinate Other Name: Butanedioic acid,1-[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl] ester;Succinic acid,mono[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] ester,(+)-;Butanedioic acid,mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl] ester,[2R-[2R*(4R*,8R*)]]-;α-Tocopherol,succinate;Butanedioic acid,mono[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl] ester;6-Chromanol,2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-,hydrogen succinate,(+)-;(+)-α-Tocopheryl succinate;α-Tocopheryl acid succinate;d-α-Tocopherol acid succinate;d-α-Tocopheryl acid succinate;α-Tocopheryl succinate;α-Tocopherol hemisuccinate;Covitol 1210;α-Tocopherol acid succinate;d-α-Tocopheryl hemisuccinate;Vitamin E hemisuccinate;Vitamin E d-α-tocosuccinate;Vitamin E acid succinate;Vitamin E succinate;CV 104;NSC 173849;α-Vitamin E succinate;Tocopherol succinate;α-Tocopheryl hemisuccinate;120246-47-1;53532-12-0;55134-51-5
CAS No.: 4345-03-3 Molecular Formula: C33H54O5
InChIKeys: InChIKey=IELOKBJPULMYRW-NJQVLOCASA-N Molecular Weight: 530.78
Exact Mass: 530.78 EC Number: 224-403-8
UNII: LU4B53JYVE DSSTox ID: DTXSID2026151
HScode: 2936280000 Categories: Vitamins and Minerals Medicines

PSA: 72.8 XLogP3: 11.88
Appearance: D-alpha-tocopheryl acid succinate is a white powder. (NTP, 1992) Density: 1.0±0.1 g/cm3
Melting Point: 76-77 °C Boiling Point: 625.8±55.0 °C at 760 mmHg
Flash Point: 187.0±25.0 °C Refractive Index: 1.498
Water Solubility: H2O: less than 0.1 mg/mL at 64° F (NTP, 1992) Storage Conditions: 2-8°C
Toxicity: 7gm/kg”>LD50 oral in rat: > 7gm/kg Air and Water Reactions: Insoluble in water.
Reactive Group: Acids, Carboxylic Reactivity Profile: D-ALPHA-TOCOPHERYL ACID SUCCINATE is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word
Hazard statement(s)

none
Precautionary statement(s)
Prevention

none
Response

none
Storage

none
Disposal

none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.