L-Pyroglutamic Acid | CAS 98-79-3 | Amino Acid as Natural Moisturizing Factor - - PREMIUM INGREDIENT

L-Pyroglutamic Acid | CAS 98-79-3 | Amino Acid as Natural Moisturizing Factor for Skin Care in Cosmetic Sector`

Categories:

Amino Acids

CAS No:

98-79-3

3 / 1

Description

Basic Info

Characteristics

Hazard Identification

Handling and Storage

Basic Information

L-Pyroglutamic Acid
Synonym	L-5-Oxoproline, L-2-Pyrrolidone-5-carboxylic acid
CAS No.	98-79-3
Molecular Formula	C₅H₇NO₃
Molecular Weight	129.11
Appearance	White crystalline powder
Assay	≥99.0%
Grade	Food Grade, Cosmetic Grade
Executive Standard	USP, AJI
Certifications	ISO9001, HALAL, KOSHER, Non-GMO

Product Overview

L-Pyroglutamic Acid, with the CAS number 98-79-3 and also referred to as L-5-oxoproline, is a naturally occurring cyclic amino acid derivative derived from L-glutamic acid. Typically produced through biological fermentation, it serves as a crucial constituent of the skin’s natural moisturizing factor, offering exceptional skin hydration and humectant capabilities. It is primarily utilized as a functional ingredient in cosmetic skincare formulations, as well as in functional foods and nutritional supplements, owing to its remarkable water-binding capacity and favorable biocompatibility.

Character

L-Pyroglutamic acid is a cyclic derivative of L-glutamic acid. It is freely soluble in water, and maintains stable chemical properties under normal storage conditions. It exists naturally in fermented food and human skin natural moisturizing factor (NMF). It has strong water retention capacity and low skin irritation, ideal for cosmetic and food raw material applications.

Main Functions

1.Powerful humectant: binds water molecules to maintain skin hydration, one of natural skin moisturizing ingredients

2.Nutritional fortifier for functional food and nutritional formulations

3.Formulation stabilizer, improves the stability of cosmetic & food systems

4.Biochemical intermediate for amino acid related synthesis

Applications

1.Cosmetic & personal care: moisturizing serum, cream, lotion, skincare raw materials

2.Food industry: functional food additives, dietary supplement raw materials

3.Biochemical field: biochemical synthesis intermediates and research usage

Packaging & Storage

Packaging: 25kg kraft paper bag with inner PE bag, customized packaging available

Storage: Keep in cool, dry, ventilated place, sealed tightly, avoid direct sunlight and high temperature.

Shelf life: 24 months under proper storage conditions.

Product Name:	L-Pyroglutamic acid	Other Name:	L-Proline,5-oxo-;Proline,5-oxo-,L-;5-Oxo-L-proline;L-5-Carboxy-2-pyrrolidinone;L-Pyroglutamic acid;L-Pyrrolidonecarboxylic acid;L-Pyrrolidinonecarboxylic acid;L-5-Oxoproline;(-)-Pyroglutamic acid;Glutimic acid;Glutiminic acid;(S)-(-)-γ-Butyrolactam-γ-carboxylic acid;2-Pyrrolidinone-5-carboxylic acid;Pyroglutamic acid;Oxoproline;Pyrrolidinonecarboxylic acid;5-Oxoproline;Pyrrolidonecarboxylic acid;Pyrrolidone-5-carboxylic acid;L-2-Pyrrolidone-5-carboxylic acid;5-Pyrrolidinone-2-carboxylic acid;L-5-Oxo-2-pyrrolidinecarboxylic acid;5-Carboxy-2-pyrrolidinone;L-Glutamic acid,γ-lactam;PCA;Ajidew A 100;2-L-Pyrrolidone-5-carboxylic acid;L-Glutimic acid;L-Glutiminic acid;(S)-Pyroglutamic acid;(S)-5-Oxo-2-pyrrolidinecarboxylic acid;Pidolic acid;(-)-2-Pyrrolidone-5-carboxylic acid;(5S)-2-Oxopyrrolidine-5-carboxylic acid;(S)-(-)-2-Pyrrolidone-5-carboxylic acid;(S)-2-Pyrrolidone-5-carboxylic acid;Pidolidone;2-Oxopyrrolidine-5(S)-carboxylic acid;Oxopyrrolidinecarboxylic acid;NSC 143034;(2S)-5-Oxopyrrolidine-2-carboxylic acid;PCA 50;(S)-5-Oxoproline;L-(-)-Pyroglutamic acid;(S)-5-Oxo-1H-pyrrolidine-2-carboxylic acid;Pyroglutamine;L-Pyroglutamine;Take Off Booster;VLS 3000-01;498-91-9;6886-28-8;16891-48-8;29222-42-2;87430-62-4;312618-42-1;95650-42-3
CAS No.:	98-79-3	Molecular Formula:	C5H7NO3
InChIKeys:	InChIKey=ODHCTXKNWHHXJC-VKHMYHEASA-N	Molecular Weight:	129.11400
Exact Mass:	129.11	EC Number:	202-700-3
NSC Number:	760414\|11742\|9966	DSSTox ID:	DTXSID6046260
HScode:	2933790090	Categories:	Amino Acids and Derivatives

PSA:	66.40000	XLogP3:	-0.8
Appearance:	White fine crystals	Density:	1.38 g/cm3
Melting Point:	184.7 °C	Boiling Point:	453.1ºC at 760 mmHg
Flash Point:	227.8ºC	Refractive Index:	-10 ° (C=5, H2O)
Water Solubility:	H2O: 10-15 g/100 mL (20 ºC)	Storage Conditions:	Store at RT.
Collision Cross Section:	130.6 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]\|121 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]\|130.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|130.1 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|124.1 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|124.6 Å² [M-H]-

Classification of the substance or mixture

Serious eye damage, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H318 Causes serious eye damage
Prevention	P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
Response	P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.