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Basic Information

L-Isoleucine
Synonym Isoleucine, L-Ile, (2S,3S)-2-Amino-3-methylpentanoic acid
CAS No. 73-32-5
EINECS No. 200-798-2
Molecular Formula C₆H₁₃NO₂
Molecular Weight 131.17
Appearance White crystalline powder
Assay 98.5% – 101.5%
Grade Food Grade, Feed Grade, Pharmaceutical Grade
Executive Standard USP, EP, JP, AJI
Certifications ISO, HALAL, KOSHER

 

Product Overview

L-Isoleucine (Cas No.: 73-32-5) is an essential branched-chain amino acid (BCAA) and one of the three BCAAs alongside L-leucine and L-valine. It is widely produced by microbial fermentation and supplied as white crystalline powder. As an essential amino acid that the human body cannot synthesize on its own, L-isoleucine is widely used in food nutrition fortification, dietary supplements, sports nutrition formulations, infant nutrition and feed additive industries. It is a key raw material for BCAA blends, amino acid infusions and nutritional fortifiers.

 

Character

L-Isoleucine is an essential α-amino acid with a hydrophobic side chain. It is sparingly soluble in water and stable under normal storage conditions. As one of the three branched-chain amino acids (BCAAs), it plays an important role in muscle metabolism, protein synthesis and energy regulation. It is produced by microbial fermentation and meets USP/EP/JP monograph requirements.

 

Main Functions

1.Essential Amino Acid Supplementation — cannot be synthesized by the human body, must be obtained from diet or supplements

2.Branched-Chain Amino Acid (BCAA) — one of the three BCAAs (leucine, isoleucine, valine), supports muscle protein synthesis

3.Sports Nutrition Support — commonly used in BCAA blends, pre/post-workout supplements and recovery formulations

4.Nutritional Fortification — fortifies amino acid profile in food, beverage and infant nutrition products

5.Feed Nutrition Enhancer — improves amino acid balance in animal feed, supports growth and development

 

Applications

 

1.Dietary Supplements — BCAA capsules, tablets, powder blends, amino acid complex formulas

2.Sports Nutrition — pre-workout, post-workout recovery drinks, protein powders, energy bars

3.Food & Beverage Fortification — functional beverages, infant formula, medical nutrition products

4.Feed Additives — livestock, poultry and aquaculture feed amino acid fortification

 

Packaging & Storage

Packaging: 25kg kraft paper bag with inner PE bag, or customized packaging

Storage: Keep in cool, dry and ventilated place, sealed tightly, avoid direct sunlight and high temperature

Shelf life: 24 months under proper storage conditions

 

Product Name: L-Isoleucine Other Name: L-Isoleucine;Isoleucine,L-;Isoleucine;erythro-L-Isoleucine;2-Amino-3-methylvaleric acid;(2S,3S)-α-Amino-β-methylvaleric acid;L-(+)-Isoleucine;[S-(R*,R*)]-2-Amino-3-methylpentanoic acid;(S)-Isoleucine;(2S,3S)-α-Amino-β-methyl-n-valeric acid;(2S,3S)-2-Amino-3-methylpentanoic acid;(S,S)-Isoleucine;2S,3S-Isoleucine;L-Norvaline,3-methyl-,erythro-;L-Ile;Pentanoic acid,2-amino-3-methyl-,(2S,3S)-;NSC 46708;Isoleucine,(2S,3ξ)-;7004-09-3;410078-51-2;501028-75-7;807611-99-0;959215-79-3;1050482-26-2;1131911-83-5;1186126-44-2;1431840-86-6;2012595-46-7;2110474-15-0;2230755-14-1
CAS No.: 73-32-5 Molecular Formula: C6H13NO2
InChIKeys: InChIKey=AGPKZVBTJJNPAG-WHFBIAKZSA-N Molecular Weight: 131.17
Exact Mass: 131.17 BRN: 1721792
EC Number: 200-798-2 HScode: 29224995
Categories: Amino Acids and Derivatives

PSA: 63.3 XLogP3: -1.7
Appearance: White to Off-white powder Density: 1.0±0.1 g/cm3
Melting Point: 285.5 °C (decomp) Boiling Point: Sublimes at 168-170 deg C
Flash Point: 168-170°C Refractive Index: 1.463
Water Solubility: H2O: 41.2 g/L (50 ºC);1 M HCl: 50 mg/mL Storage Conditions: Store at RT.
Vapor Pressure: 6.85X10-9 mm Hg at 25 deg C (est) Toxicity: LD50 intraperitoneal in rat: 6822mg/kg
Specific rotation: 41 º (c=4, 6N HCl) Taste: Bitter
PKA: 2.37(at 0 °C)

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word

Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.