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Honokiol  is an organic compound that is a lignan component isolated from the traditional Chinese medicine Houpu. It exists in the bark of Magnolia officinalis Rehder et Wilson and Magnolia obovata Thunb. plants in the Magnolia family. Honokiol has central muscle relaxant activity, long-lasting effects, and pharmacological effects such as antibacterial, anti-inflammatory, anti microbial, anti ulcer, antioxidant, anti-aging, anti-tumor, and cholesterol lowering. In terms of antibacterial activity, honokiol has significant antibacterial activity against Gram positive bacteria, acid resistant bacteria, and filamentous fungi, and has a more significant antibacterial effect on Streptococcus mutans, with the strongest inhibitory effect on Staphylococcus.

 

Applications of Honokiol

As the medicine of anti-inflammatory, antibacterial, antioxidant and anti-tumor drug, it is widely used in the fields of medicine and health products;

* As a strong antioxidant, it is widely used in the cosmetics industry. Magnolol is a powerful antioxidant in cardiovascular diseases.

* Honokiol is widely used as a functional food additive;

* Honokiol can be used as raw material added to healthy food, the purpose is to enhance immunity and resist melancholy;

* A powerful antioxidant in cardiovascular diseases, 1000 times more protein than vitamin E in inhibiting lipid peroxidation.

* A major contributor to atherosclerosis and heart disease.

* Honokiol is effective in cardiovascular diseases.

* Also widely used in the cosmetics and pharmaceutical industry.

 

Functions of Honokiol

1. Honokiol can inhibit the secretion of acidity, anti-dental caries, and anti-periodontal disease.

2. Anti-tumor and cancer: Inhibits or prevents the growth or development of malignant cells. A potential anti-cancer material.

3. Anti-anxiety: Relaxes striated muscles, reduces blood pressure, anti-depressive and improves sleep.

4. Powerful antioxidant protection: 1000 times more potent than vitamin E in inhibiting lipid peroxidation, a major contributor to atherosclerosis and heart diseases.

Product Name

Honokiol extracted from Magnolia Officinalis Bark

Source

Magnolia Officinalis Bark

Assay

98% (HPLC)

Active ingredient

Honokiol

Molecular Formula

C18H18O2

Molecular Weight

266.33

 CAS NO.

35354-74-6

 CAS NO.

35354-74-6

Appearance

White fine powder

Certificate

Halal, Kosher, ISO

Shelf Life

24 months

 

 

 

Product Name: Honokiol Other Name: [1,1′-Biphenyl]-2,4′-diol,3′,5-di-2-propen-1-yl-;[1,1′-Biphenyl]-2,4′-diol,3′,5-di-2-propenyl-;3′,5-Di-2-propen-1-yl[1,1′-biphenyl]-2,4′-diol;Honokiol;3′,5-Diallyl-2,4′-biphenyldiol;NSC 293100;2-[4-Hydroxy-3-(2-propenyl)phenyl]-4-(2-propenyl)phenol;2-Allyl-4-(5-allyl-2-hydroxyphenyl)phenol
CAS No.: 35354-74-6 Molecular Formula: C18H18O2
InChIKeys: FVYXIJYOAGAUQK-UHFFFAOYSA-N Molecular Weight: 266.3
Exact Mass: 266.130679813 UNII: 11513CCO0N
NSC Number: 293100 DSSTox ID: DTXSID30188845
HScode: 2907299090 Categories: Plant Extracts

Classification of the substance or mixture

Serious eye damage, Category 1

GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H318 Causes serious eye damage

Precautionary statement(s)
Prevention

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…

Response

P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P317 Get medical help.

Storage

none

Disposal

none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.