| Product Name: | Camptothecin | Other Name: | 1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-,(4S)-;Camptothecine;1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-,(S)-;(4S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Camptothecin;20(S)-Camptothecine;d-Camptothecin;NSC 94600;(S)-Camptothecin;20(S)-Camptothecin;(+)-Camptothecin;(+)-Camptothecine;MAG-CPT;Campathecin;(S)-(+)-Camptothecin;S-CKD 602;30628-51-4;157405-40-8 |
| CAS No.: | 7689-03-4 | Molecular Formula: | C20H16N2O4 |
| InChIKeys: | InChIKey=VSJKWCGYPAHWDS-FQEVSTJZSA-N | Molecular Weight: | 348.35 |
| Exact Mass: | 348.35 | EC Number: | 444-280-6 |
| UNII: | XT3Z54Z28A | NSC Number: | 94600 |
| DSSTox ID: | DTXSID0030956 | NCI Thesaurus Code: | C338 |
| HScode: | 29399990 | Categories: | Plant Extracts |
| PSA: | 79.7 | XLogP3: | 1 |
| Appearance: | yellow solid | Density: | 1.5±0.1 g/cm3 |
| Melting Point: | 255-277 °C (decomp) | Boiling Point: | 757.0±60.0 °C at 760 mmHg |
| Flash Point: | 411.6±32.9 °C | Refractive Index: | 1.746 |
| Water Solubility: | H2O: insoluble ;chloroform/methanol (4:1): 4 mg/mL | Storage Conditions: | 2-8°C |
| Toxicity: | Oral-rat LD50: 153 mg/kg; Oral-Mouse LD50: 50.1 mg/kg | Flammability characteristics: | Thermal decomposition emits toxic nitrogen oxide fumes; reacts with acids to decompose |
| Specific rotation: | D25 +31.3° (in chloroform-methanol, 8:2) | Collision Cross Section: | 181.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
Classification of the substance or mixture
Acute toxicity – Category 3, Oral
GHS label elements, including precautionary statements
| Pictogram(s) |  |
|---|---|
| Signal word |
Danger |
| Hazard statement(s) |
H301 Toxic if swallowed |
| Precautionary statement(s) | |
| Prevention |
P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. |
| Response |
P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see … on this label). P330 Rinse mouth. |
| Storage |
P405 Store locked up. |
| Disposal |
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
Other hazards which do not result in classification
no data available
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.