L-Tryptophan | CAS 73-22-3 | Amino Acid for Feed & Food - - PREMIUM INGREDIENT

L-Tryptophan | CAS 73-22-3 | Essential Amino Acid for Animal Feed, Food and Pharmaceutical Use

Categories:

Amino Acids

CAS No:

73-22-3

4 / 1

Description

Basic Info

Characteristics

Hazard Identification

Handling and Storage

Basic Information

L-Tryptophan
Synonym	L-Tryptophane, (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid
CAS No.	73-22-3
Molecular Formula	C₁₁H₁₂N₂O₂
Molecular Weight	204.23
Appearance	White or off-white crystalline powder
Assay	98.5% – 101.5%
Available Grade	Feed Grade, Food Grade, Pharmaceutical Grade
Executive Standard	USP, AJI, FCC, Feed Special Standard
Certifications	ISO9001, HALAL, KOSHER, FAMI-QS, Non-GMO

Product Overview

L-Tryptophan (Cas No.: 73-22-3) is an essential aromatic amino acid produced by microbial fermentation, presented as white or off-white crystalline powder. As an indispensable nutrient substance that cannot be synthesized by living organisms, it is widely used as a key nutritional fortifier. It serves as an important amino acid additive for animal feed formulation, and is also applied in functional food and dietary supplement production for body nutrition regulation. Additionally, it can be used as a raw material for pharmaceutical intermediate preparation.

Character

L-Tryptophan is a stable aromatic essential amino acid with indole ring structure. It is slightly soluble in water and maintains stable physical and chemical properties under cool, dry and sealed storage environments. Adopting advanced microbial fermentation technology, the product features high purity, low impurities and stable batch quality.

It is a critical limiting amino acid for animal nutrition and an important nutritional amino acid for human body metabolism. It acts as a synthetic precursor of serotonin and melatonin, participating in multiple physiological regulation processes. The product adapts to industrial production requirements of feed fortification, food nutrition supplementation and fine pharmaceutical processing.

Main Functions

1. Optimize Animal Feed Nutrition

L-Tryptophan is a vital limiting amino acid for livestock and poultry breeding. Conventional plant-based feed materials are commonly deficient in tryptophan. Reasonable supplementation of L-Tryptophan can balance the overall amino acid structure of feed formulas, make up for nutritional deficiencies in daily feed, and greatly improve feed digestibility and utilization efficiency.

It effectively promotes the growth and development of livestock, poultry and aquatic animals, increases daily weight gain, and improves animal feeding status and survival rate. Meanwhile, it can reduce the addition proportion of high-protein raw materials in feed, lower feeding cost, and optimize the scientific collocation of low-protein feed formulas, which is an essential additive in modern precision breeding industry.

2. Human Body Nutritional Regulation & Fortification

As an essential amino acid for human body, L-Tryptophan participates in human protein synthesis and metabolic regulation. It is the core precursor substance for synthesizing serotonin and melatonin in the human body, helping maintain normal nervous system function and healthy sleep state. It is widely used in compound amino acid nutrition formulas to supplement daily dietary amino acid deficiency.

3. Pharmaceutical Raw Material Application

L-Tryptophan can be used as a basic raw material for pharmaceutical amino acid preparations and biological intermediates, applied in fine pharmaceutical production.

Applications

1. Animal Feed Industry

This is the primary application field of L-Tryptophan. It is widely added in feed for pigs, poultry, ruminants and aquatic products. It improves the amino acid balance of feed, solves the problem of insufficient natural tryptophan in plant feed, enhances feed conversion efficiency, promotes animal growth and improves breeding economic benefits. It is suitable for large-scale industrial feed production and low-protein feed formula optimization.

2. Functional Food & Dietary Supplements

L-Tryptophan is used for nutritional fortification of functional food, health care products and compound amino acid supplements. It is applied in nutritional powder, functional beverage and customized dietary formula products to supplement essential amino acids and assist physical state regulation.

3. Pharmaceutical Industry

Applied in the preparation of amino acid infusion, health pharmaceutical intermediates and related biological fine chemical products for medical nutritional supplementation.

Packaging & Storage

Packaging: 25kg kraft paper bag with inner PE plastic bag, customized packaging is acceptable.

Storage: Store in cool, dry, ventilated warehouse, keep tightly sealed, avoid high temperature, direct sunlight and damp environment.

Shelf Life: 24 months under standard storage conditions.

Product Name:	L-Tryptophan	Other Name:	L-Tryptophan;Tryptophan,L-;l-β-3-Indolylalanine;Tryptophane;Tryptophan;L-Tryptophane;1H-Indole-3-propanoic acid,α-amino-,(S)-;L-(-)-Tryptophan;l-α-Aminoindole-3-propionic acid;2-Amino-3-indolylpropanoic acid;(S)-α-Aminoindole-3-propionic acid;(-)-Tryptophan;1H-Indole-3-alanine,(S)-;EH 121;(S)-Tryptophan;(S)-α-Amino-1H-indole-3-propanoic acid;(S)-α-Amino-β-indolepropionic acid;3-Indol-3-ylalanine;L-Alanine,3-(1H-indol-3-yl)-;Lyphan;NSC 13119;(2S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(2S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(2S)-2-Azaniumyl-3-(1H-indol-3-yl)propanoate;6912-86-3;80206-30-0;154635-35-5;2416148-24-6
CAS No.:	73-22-3	Molecular Formula:	C11H12N2O2
InChIKeys:	InChIKey=QIVBCDIJIAJPQS-VIFPVBQESA-N	Molecular Weight:	204.22500
Exact Mass:	204.23	EC Number:	200-795-6
UNII:	8DUH1N11BX	NSC Number:	757373
DSSTox ID:	DTXSID5021419	NCI Thesaurus Code:	C29603
Color/Form:	Leaflets or plates from dilute alcohol\|White to slightly yellowish-white … crystals or crystalline powder	ATC Code:	N – Nervous system
HScode:	2933990090	Categories:	Amino Acids and Derivatives

PSA:	79.11000	XLogP3:	-1.1
Appearance:	L-tryptophan is a white powder with a flat taste. An essential amino acid; occurs in isomeric forms. (NTP, 1992)	Density:	1.4±0.1 g/cm3
Melting Point:	282 °C	Boiling Point:	447.9°C at 760 mmHg
Flash Point:	224.7±25.9 °C	Refractive Index:	1.698
Water Solubility:	H2O: 13.4 mg/mL at 25 °C	Storage Conditions:	Protect from light
Vapor Pressure:	2.1X10-9 mm Hg at 25 deg C (est)	Toxicity:	LD508mmol / kg (rat, intraperitoneal injection). It is safe when used in food (FDA, §172.320, 2000).
Specific rotation:	Specific optical rotation: -31.5 deg at 23 °C/D (water, 1%), +2.4 deg at 20 °C/D (hydrochloric acid, 0.5 N); +0.15 deg at 20 °C/D (sodium hydroxide, 2.43% in 0.5 N)	Odor:	Odorless
Taste:	FLAT TASTE	PH:	A 1% solution in water has a pH of 5.5 to 7.
PKA:	7.38(at 25 °C)	Dissociation Constants:	7.38 (at 25 °C)\|pK1 = 2.38 /SRC: carboxylic acid/; pK2 = 9.39 /SRC: primary amine/
Collision Cross Section:	154.22 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]\|158.58 Å² [M-H]- [CCS Type: DT, Method: stepped-field]\|145 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]\|150.1 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|150.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|147.6 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|147.7 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|142.3 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|142.5 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|151.5 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]\|149.1 Å² [M-H]-	Experimental Properties:	Decomposes at 289 °C (rapid heating)\|Needles from methanol, decomposes at 251 °C /Tryptophan hydrochloride/\|UV: 3453 (Sadtler Research Laboratories Spectral Collection) /Tryptophan (DL)/
Air and Water Reactions:	Slightly soluble in water.	Reactive Group:	Salts, Acidic
Reactivity Profile:	Acidic salts, such as L-TRYPTOPHAN, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH’s of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Protect from light