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| Product Name: | L-Tryptophan | Other Name: | L-Tryptophan;Tryptophan,L-;l-β-3-Indolylalanine;Tryptophane;Tryptophan;L-Tryptophane;1H-Indole-3-propanoic acid,α-amino-,(S)-;L-(-)-Tryptophan;l-α-Aminoindole-3-propionic acid;2-Amino-3-indolylpropanoic acid;(S)-α-Aminoindole-3-propionic acid;(-)-Tryptophan;1H-Indole-3-alanine,(S)-;EH 121;(S)-Tryptophan;(S)-α-Amino-1H-indole-3-propanoic acid;(S)-α-Amino-β-indolepropionic acid;3-Indol-3-ylalanine;L-Alanine,3-(1H-indol-3-yl)-;Lyphan;NSC 13119;(2S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(2S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(2S)-2-Azaniumyl-3-(1H-indol-3-yl)propanoate;6912-86-3;80206-30-0;154635-35-5;2416148-24-6 |
| CAS No.: | 73-22-3 | Molecular Formula: | C11H12N2O2 |
| InChIKeys: | InChIKey=QIVBCDIJIAJPQS-VIFPVBQESA-N | Molecular Weight: | 204.22500 |
| Exact Mass: | 204.23 | EC Number: | 200-795-6 |
| UNII: | 8DUH1N11BX | NSC Number: | 757373 |
| DSSTox ID: | DTXSID5021419 | NCI Thesaurus Code: | C29603 |
| Color/Form: | Leaflets or plates from dilute alcohol|White to slightly yellowish-white … crystals or crystalline powder | ATC Code: | N – Nervous system |
| HScode: | 2933990090 | Categories: | Amino Acids and Derivatives |
| PSA: | 79.11000 | XLogP3: | -1.1 |
| Appearance: | L-tryptophan is a white powder with a flat taste. An essential amino acid; occurs in isomeric forms. (NTP, 1992) | Density: | 1.4±0.1 g/cm3 |
| Melting Point: | 282 °C | Boiling Point: | 447.9°C at 760 mmHg |
| Flash Point: | 224.7±25.9 °C | Refractive Index: | 1.698 |
| Water Solubility: | H2O: 13.4 mg/mL at 25 °C | Storage Conditions: | Protect from light |
| Vapor Pressure: | 2.1X10-9 mm Hg at 25 deg C (est) | Toxicity: | LD508mmol / kg (rat, intraperitoneal injection). It is safe when used in food (FDA, §172.320, 2000). |
| Specific rotation: | Specific optical rotation: -31.5 deg at 23 °C/D (water, 1%), +2.4 deg at 20 °C/D (hydrochloric acid, 0.5 N); +0.15 deg at 20 °C/D (sodium hydroxide, 2.43% in 0.5 N) | Odor: | Odorless |
| Taste: | FLAT TASTE | PH: | A 1% solution in water has a pH of 5.5 to 7. |
| PKA: | 7.38(at 25 °C) | Dissociation Constants: | 7.38 (at 25 °C)|pK1 = 2.38 /SRC: carboxylic acid/; pK2 = 9.39 /SRC: primary amine/ |
| Collision Cross Section: | 154.22 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|158.58 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|145 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|150.1 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|150.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|147.6 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|147.7 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|142.3 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|142.5 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|151.5 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|149.1 Ų [M-H]- | Experimental Properties: | Decomposes at 289 °C (rapid heating)|Needles from methanol, decomposes at 251 °C /Tryptophan hydrochloride/|UV: 3453 (Sadtler Research Laboratories Spectral Collection) /Tryptophan (DL)/ |
| Air and Water Reactions: | Slightly soluble in water. | Reactive Group: | Salts, Acidic |
| Reactivity Profile: | Acidic salts, such as L-TRYPTOPHAN, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH’s of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions. |
Classification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
| Pictogram(s) | No symbol. |
|---|---|
| Signal word |
No signal word |
| Hazard statement(s) |
none |
| Precautionary statement(s) | |
| Prevention |
none |
| Response |
none |
| Storage |
none |
| Disposal |
none |
Other hazards which do not result in classification
no data available
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Protect from light