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Basic Information

Product Name Disodium 5′-Ribonucleotides (I+G)
Composition

IMP (Disodium 5′-Inosinate)

GMP (Disodium 5′-Guanylate)

E Number E635

CAS Number

4691-65-0 (IMP) 

5550-12-9 (GMP)

Molecular Formula

C₁₀H₁₁N₄Na₂O₈P (IMP)

C₁₀H₁₂N₅Na₂O₈P (GMP)

Appearance White to off-white crystalline powder
Solubility Freely soluble in water
Grade Food Grade
Assay (IMP+GMP, dry basis) 97.0% – 102.0%
IMP Content 48.0% – 52.0%
GMP Content 48.0% – 52.0%
Loss on Drying ≤25.0%
Transmittance (5% aqueous solution) ≥95.0%
pH (5% aqueous solution) 7.0 – 8.5

Product Overview

Disodium 5′-Ribonucleotides, commonly known as I+G (E635), is a 1:1 blend of disodium 5′-inosinate and disodium 5′-guanylate. It acts as a powerful umami flavor enhancer with strong synergistic effect when combined with MSG, helps reduce salt content and mask undesirable off-flavors. It is widely used in processed meat, seasonings, instant food, snacks and sauces.

Recommended Dosage

The addition amount depends on food categories, formula requirements and local food regulations.

1.Compound seasonings: 0.1% – 1.0%

2.Meat products: 0.05% – 0.5%

3.Soup & instant food: 0.02% – 0.3% Common blending ratio: MSG : I+G = 10:1 ~ 20:1.

Final dosage should be confirmed according to formulation test and regional food compliance standards.

Key Characteristics

1.Powerful umami enhancer, significantly boosts meaty, brothy and savory notes

2.Strong synergistic effect with MSG, multiplies umami intensity at very low dosage

3.Helps reduce salt content while maintaining desired flavor profile

4.Masks undesirable bitter, metallic and raw off-notes in food formulations

5.Good thermal stability under cooking, steaming and sterilization conditions

6.White to off-white crystalline powder, easy to dissolve and blend

 

Main Functions

Umami Flavor Enhancer: Intensifies savory, meaty and brothy taste, making food more flavorful and satisfying.

MSG Synergist: Works together with monosodium glutamate to multiply umami effect, reducing total MSG usage.

Salt Reduction Agent: Enables lower sodium formulations without compromising taste.

Off-Note Masker: Suppresses bitter, metallic and raw flavors, resulting in a smoother, more rounded taste.

Flavor Stabilizer: Helps maintain consistent flavor profile during processing and shelf life.

 

Applications

Processed Meat Products Core application, widely used in ham, sausage, cured meat and ready-to-eat meat products to enhance meaty flavor.

Seasonings & Sauces Applied in chicken bouillon, soy sauce, oyster sauce, hot pot base, soup stock and compound seasonings.

Instant Food Used in instant noodles, instant soup packets and ready-to-eat meal seasonings.

Snacks & Convenience Food Applied in potato chips, puffed snacks, seasoned nuts and popcorn flavoring powders.

Canned Food & Prepared Dishes Used in canned vegetables, ready meals and frozen prepared foods to boost savory taste.

Vegetarian & Plant-based Products Added to plant-based meat substitutes and vegetarian sauces to improve umami profile.

Packaging and Storage

Packaging: 25 kg net multi-paper Kraft bag with inner polyethylene liner

Storage: Store in a cool, dry, well-ventilated area; keep tightly sealed away from moisture and strong odors

Shelf Life: 24 months from date of manufacture under proper storage conditions

Product Name: Disodium 5′-inosinate Other Name: 5′-Inosinic acid,sodium salt (1:2);5′-Inosinic acid,disodium salt;Disodium inosinate;Disodium 5′-inosinate;Disodium inosine 5′-phosphate;Sodium inosinate;Inosine 5′-monophosphate disodium;Disodium IMP;IMP disodium salt;Disodium inosine 5′-monophosphate;Inosine 5′-monophosphoric acid disodium salt;IMP sodium salt;Sodium 5′-inosinate;Inosine 5′-monophosphate disodium salt;5′-IMP di-Na salt;5′-IMP disodium salt;Inosine monophosphate disodium salt;Disodium 5′-IMP;E 631;NSC 20263;E 631 (food enhancement agent);133749-71-0;6757-07-9;398516-04-6
CAS No.: 4691-65-0 Molecular Formula: C10H13N4O8P.2Na
InChIKeys: InChIKey=SLIUELDPAPMQIB-IDIVVRGQSA-N Molecular Weight: 392.17
Exact Mass: 392.010989 EC Number: 225-146-4
DSSTox ID: DTXSID4044242 HScode: 29349990
Categories: Food Flavorings

PSA: 186 XLogP3: -1.27550
Appearance: White Crystalline Powder Density: 2.31g/cm3
Melting Point: 175 °C Boiling Point: 851.4ºC at 760 mmHg
Flash Point: 468.7ºC Water Solubility: Soluble in water, sparingly soluble in ethanol, practically insoluble in ether
Storage Conditions: 2-8°C PH: Between 7,0 and 8,5

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word

Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.