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Product Name: BERBERINE HCL

CAS No.: 633-65-8

Molecular formula: C20H18CLNO4•2H2O

molecular weight: 407.85

Conforms to: CP2005, CP2020, JP17

Botanical source: Coptis chinensis, Phellodendron chinense and Tripterygium wilfordii

Appearance: Yellow crystalline powder

Efficacy: antibacterial, anti-inflammatory

Use: It is widely used to treat gastroenteritis, bacillary dysentery, etc. It also has a certain effect on tuberculosis, scarlet fever, acute tonsillitis and respiratory tract infections.

Packaging: 25Kg/drum lined with 2 layer food grade plastic bag.

BERBERINE HCL

 

Character

Yellow crystalline   powder; Odorless   and tasteless

 

Identification

1) Color Reaction   A

2) Color Reaction   B

3) Color Reaction   C

4)   IR

5)   Chloride

 

Solubility

Soluble   in hot-water,   slightly   soluble  in   water   or   ethanol,   insoluble in   aether.

 

Loss on Drying

  12.00%

 

Residue on Ign ition

  0.20%

 

Berberine   HCL,Dried basis

  97.00%

 

Jatrorrhizine

  1.00%

 

Palmatine

  1.00%

 

Total other impu rities

≤ 2.00%

 

Heavy metals

≤ 20.00ppm

 

Storage

Preserve in well-closed containers,store in cool and dry place,protected fr om   light.

Product Name: Berberine hydrochloride Other Name: Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-,chloride (1:1);Berbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-,chloride;Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-,chloride;Berberine,chloride;Berberine hydrochloride;Berberinium chloride;NSC 646666;NSC 163088;Berberine IR;16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride;1082532-96-4
CAS No.: 633-65-8 Molecular Formula: C20H18NO4.Cl
InChIKeys: InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M Molecular Weight: 371.81400
Exact Mass: 371.09200 EC Number: 211-195-9
UNII: UOT4O1BYV8 NSC Number: 757795|163088|646666
DSSTox ID: DTXSID8024602 NCI Thesaurus Code: C87331
HScode: 3003409000 Categories: Antibiotics

PSA: 40.80000 XLogP3: 0.10030
Appearance: yellow crystalline powder Density: 1.654g/cm3
Melting Point: 214 °C Water Solubility: soluble in cold water
Storage Conditions: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from Toxicity: 15 g/kg KSRNAM 8,654,74″>LD50 orl-rat: >15 g/kg KSRNAM 8,654,74
Collision Cross Section: 175.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word

Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

Other hazards which do not result in classification

no data available

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.